Milestone microwave synthesis systems
Microwave-enhanced
synthesis represents a fundamental step forward in the capabilities of synthetic chemistry. It allows organic chemists to work faster, generating higher yields with increased product purity, and to scale experiments
up reliably from milligrams to much larger quantities without the need to alter reaction parameters. It offers much more precise control over conditions of temperature and pressure than any previous technology.
Ultimately, by eliminating much of the time and effort from the process of performing chemical reactions, it allows chemists to focus on what is most important—the development of new compounds, or refined
methods for generating known products.
The Milestone advantage in organic synthesis resides in the ability to provide thorough and effortless scalability and uniquely offer tools to work with the entire range of
volumes in the synthetic process, from discovery, through parallel synthesis, to large-scale production.
The StartSYNTH is a flexible system that has been developed to offer microwave enhanced synthesis to
Academia through to research laboratories. Options include ambient pressure reflux reactors using standard laboratory glassware and high pressure rotors
The MicroSYNTH allows synthesis in both open and closed vessels where reactions can be optimised in small
volumes and then taken to a larger scale in the same microwave using either batch or single large volume vessels
The RotoSYNTH is a unique system that rotates the reaction vessel at 45oand permits
microwave heating of viscous and even solid materials. Options include vessels up to 2L, inert gas reactions, and a vacuum module for removal of evolved organics and solvents
The FlowSYNTH is a continuous flow-through system with a vertical reactor. Reagents are pumped in from the
bottom of the reactor and the reaction products are collected from the top via a water cooled heat exchanger. In-line sensors ensure complete safe operating conditions
