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Telephone 0191 518 1855
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Milestone microwave rotors and sensors
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Milestone offers a wide variety of vessels for all applications from digestion, synthesis, extraction, evaporation, fusion, and protein hydrolysis The vessel technology is continuously enhanced to provide analysts with the latest tools for their application. Coupled with the extensive range of rotors are the reaction monitoring sensors
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Milestone 'vent-and-reseal' vessels are the foundation of it's microwave digestion
technology. This patented technology provides analysts with unsurpassed performance capabilities. While other devices use membranes or burst disks that render a vessel useless after venting, the Milestone system
releases only the excess pressure from the vessels. This vessel technology is the perfect complement to the EthosEZ pressure-responsive door, resulting in the safest microwave system available today
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MDR Technology
The
'dome-shaped' spring at the top of the vessel is temporarily flattened in case of overpressure (1), allowing the cap to lift-up (2) slightly and release the pressure. Once the pressure has been released,
the cap closes again (3), and the microwave program can continue. This ensures total safety and a successful completion of the digestion/extraction process
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Comparison of burst disk venting and Milestone 'vent and reseal' venting technology
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Burst disk venting
When a
specific pressure is achieved, the disk bursts, and the pressure dramatically drops to zero. Sample is lost, and the program must be manually stopped
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Milestone unique vent-and-reseal venting
Only the excess pressure is released from the vessel, and the digestion process can be completed in full safety
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Flexible Applications
A wide range of vessels are available from Milestone, to accommodate all sample preparation requirements
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Rotor Type
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Vessels nr.
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Vessel material
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Vessel volume
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Max. Temperature
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Max. Pressure
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SK-12
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12
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TFM
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100 ml
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260 °C
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35 bar
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SK-10
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10
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TFM
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100 ml
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300 °C
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100 bar
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Nova-10
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10
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TFM
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75 ml
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300 °C
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100 bar
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PRO-16
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16
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TFM
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75 ml
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200 °C
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30 bar
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PRO-24
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24
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TFM
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75 ml
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200 °C
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30 bar
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MULTIPREP
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42
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PFA
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65 ml
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200 °C
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20 bar
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Rotors with vent and reseal technology
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Multiprep 41: High Throughput Rotor
The Milestone Multiprep-41 is a new high throughput rotor, suitable for the microwave acid digestion of any sample requiring moderate temperature and pressure conditions - typically 200°C and 20
bar - for a full recovery of the analytes of interest. The most typical applications of the Multiprep-41 include the sample preparation of environmental samples (soil, sludge, waste water - according to
the US EPA methods 3015a, 3051a and 3052-, filters), of biological samples (tissues, food, feed, plants, agriculture products), and many others, such as paint chips and mineral leaches
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Q-20 Quartz Rotor
The
new Milestone Q-20 Quartz rotor truly opens a new era in microwave digestion, and is a fundamental addition to the outstanding capabilities of the Ethos 1 and the Start D units. The Q-20 offers elevated
performance specifically for ultra-trace analysis, unsurpassed ease of use, and full control of all digestion parameters in all vessels. It allows for the complete digestion of a variety or organic
samples, such as food and feed, plants, polymers, pharmaceuticals, clinical materials, biologicals, and oils
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Other optional rotors and systems
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Open vessel digestion
The
MOD-8 rotor allows for the simultaneous open-vessel digestion of up to eight samples, in 250 ml glass or quartz vessels. The entire rotor is composed of ultra-pure, chemically inert PTFE and PP polymers,
to minimize contamination. The individual vessels are isolated, each with its own separately connected vacuum exhaust line, so there is no risk of cross contamination. Furthermore, each vessel is also
individually connected to the automated dosing system, to ensure precise control over the distribution of acid to each sample
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Fusion rotor -
The
MultiFAST-4 consists of a muffle furnace, which perfectly fits the microwave cavity of the EthosEZ and of the START D. This represents a significant innovation and enhancement for the consolidated
capabilities of these microwave labstations by extending their application flexibility. A variety of difficult samples, such as cements, ores, slag, sediments, soils, feldspatic rocks,
ceramics, pigments and glasses, quartz can be successfully prepared for XRF, AA and ICP analysis. A temperature of up to 1000°C is reached within few minutes and the entire fusion process is completed in
less than 10 minutes. The MultiFAST-4 offers extremely fast heating rate, unique application possibilities, and unsurpassed ease of use
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Microwave evaporation system
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The Milestone evaporation system provides the tools for conveniently heating materials in
a microwave field under controlled vacuum conditions. The MMR modular microwave rotor is used for heating materials in a microwave field under controlled vacuum conditions. When connected to an external vacuum
supply (VAC-100 or VAC-2000 modules), and depending on the specific configuration, the MMR rotor can be used for vacuum assisted sarnple drying, acid removal, volume reduction, and solvent evaporation. The MMR Rotor
is a specially engineered fixture for accommodating either 8 or 12 microwave vessels. Each vessel is isolated from the others, so there is no cross contamination. Samples are processed in a clean, inert environment
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Features
- Low-temperature, safe evaporation and concentration of acids and organic solvents
- No sample transfer: evaporation takes place in the same vessel used for digestion
- Evaporation of polar and non-polar organic solvents (e.g. Hexane) after organic solvent extraction
- Rapid evaporation and concentration: 200 mL of acids (HC1, HF, HN03, etc.) evaporated in 30-90 minutes
- Sample drying before extraction or digestion
- Available as an eight (8) or twelve (12) position fixture
- Accommodates all Milestone's TFM vessels of all digestion rotors
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VAC-1000
Efficient use of
a microwave labstation for volume reduction requires a safe and reliable source of vacuum. The VAC-1000 module meets every criteria for these demanding applications. A high performance, full PTFE vacuum
pump, draws evaporated acid vapours where they are efficiently recovered in a water cooled condenser. Any remaining vapours pass through a high capacity, acid neutralisation module. Designed for safety
and durability, the system is completely enclosed with key modules clearly visible and with a rninimum of vacuum connections. The VAC-1000 module is a high performance system that integrates a vacuum
pump, a water cooled condenser and a neutralizing module to completely neutralise and/or recover acid vapors. It is the perfect complement to the MMR rotors for volume reduction and/or acid removal from
digestate samples in Milestone's Microwave Labstations
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VAC-2000
The VAC-2000
module is a high performance system that integrates a vacuum pump, a water cooled condenser and a pressurised module to completely recover organic solvents. It is the perfect complement to
Milestone's MMR rotors for volume reduction and solvent recovery. A high performance, PTFE vacuum pump draws evaporated solvent vapours through the VAC-2000 module where they are efficiently
condensed and collected in a water cooled, glass condenser. Any remaining vapours are compressed to increase the boiling point. This feature allows almost 100% solvent recovery. Designed for safety and
durability, the system is completely enclosed with key modules clearly visible and with a minimum of vacuum connections
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Microwave protein hydrolysis system
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The accuracy and precision of amino acid analysis is often determined by the quality of
protein hydrolysis. The widely used hydrolysis protocol requires heating samples in 6N HCl at 110 °C for 24 hours or more. The Milestone microwave-assisted protein hydrolysis system reduces this time to 10–30
minutes, by processing samples at elevated temperatures (up to 200 °C). This effectively eliminates the bottleneck in amino acid analysis. The protein hydrolysis system consists of a special reactor with connections
for vacuum/inert gas purging, plus temperature measurement and control. Samples are introduced into vials and loaded into a teflon rack. Hydrochloric acid is added to the reactor, where the vial rack is then placed.
The reactor is sealed, air is removed, and nitrogen gas is purged into the reactor. Microwave heating produces acid vapour that hydrolyses samples inside the vials.
Each hydrolysis reactor can accommodate either
a large single sample or multiple smaller reaction vials in a rack inside the reactor. The reactor cover supports temperature monitoring (pressure monitoring is also available). Two additional openings in the cover
provide inert gas flushing of the reactor vessel. The 0.5 litre hydrolysis reactor incorporates a cooling jacket. Connections allow the convenient flow of air or water through the jacket, after the completion of the
microwave heating cycle, to rapidly cool the reactor and contents
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Features
- Hydrolysis time reduced from 24-96 hours to 5-30 minutes increasing sample throughput
- Uniformity of temperature conditions prevents variations between samples and assures precision of results
- Inert, anaerobic processing preventing oxidative degradation of amino acids
- Hydrolysis performed in standard HPLC autosampler vials eliminating sample transfer steps
- Minimal sample handling reduces contamination and losses
- Milestone software ensures all hydrolysis parameters are stored for data validation
- Reactor sample racks can be customised to accomodate user specific vials
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Microsampling Vials and Holders
Milestone offers a choice of reaction vials and vial holders for use in its hydrolysis reactors.
Alternatively, a customised holder can be specified to accommodate vials of the required specification
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Advanced Reaction Sensors
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The Milestone microwave systems can be used with a variety of advanced
reaction sensors, including contact-less temperature and pressure control in all vessels, and direct temperature and pressure control in a single reference vessel
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